The evolution of non invasive prenatal screening
is the first non-invasive prenatal test that screens for both de novo and inherited single-gene disorders.
Current non-invasive prenatal tests screen for aneuploidies and microdeletions. PrenatalSafe® Karyo also screens for rare aneuploidies and segmental chromosome imbalances (gains and losses) in every chromosome in the fetal genome, providing karyotype-level insight.
GeneSafe™ goes further.
Through cfDNA analysis from maternal plasma, it screens for several clinically significant and life-altering genetic disorders that are not screened for with current NIPT technology.
facilitates early diagnosis for single-gene disorders
A simple blood sample (8-10 ml) collected at
10∧ weeks of gestation is required
It is a non-invasive test, no risk for the fetus and the mother.
Sensitivity and specificity > 99,9%
Falsi positivi < 0.1%
Turnaround time of just 10-15 days
GeneSafe™ involves 3 different levels of screening:
The most comprehensive information available from a noninvasive prenatal test to date
works as a complementary screen to traditional or genome-wide NIPT (such as PrenatalSafe® Karyo), allowing a more complete picture of the risk of a pregnancy being affected by a genetic disorder.
Indication for testing
The first prenatal test suitable for any type of pregnancy
GeneSafe™ test is intended for patients who meet any of the following criteria:
• advanced paternal age (men that are >40 years
• abnormal ultrasound finding(s)
suggestive of monogenic disorder
carrier of mutations in one of the common
• patients wishing to
avoid an invasive diagnostic procedure
The test is suitable for:
• both single and twin pregnancies
whose pregnancies have been achieved by IVF
techniques, including pregnancies with egg
donation or surrogacy.
Clear test results reporting
GeneSAFE™ Sample lab report
Advanced technology that ensures high reliability of the results
is a test of
Advanced molecular diagnostics solutions using state-of-the art technologies
Test performed in Italy (Rome or MIlan)
20 years experience in prenatal molecular diagnostics
ISO 17025 accredited
Over 200.00 genetic tests/year
for families and physicians
How to order
A simple "step by step" procedure for
ordering GeneSAFE™ test
Ordering GeneSafe™ test is simple and fast
Please contact a member of our Customers Service team at +39068811270 for more information or fill in all required information into the following form.